Although initially known for its biotech origins, ETHZilla‘s strategic pivot to Ethereum treasury management has captured significant market attention, surging its stock by nearly 90% following the revelation of Peter Thiel’s 7.5% stake and the disclosure of an 82,186 ETH corporate treasury. Formerly operating as 180 Life Sciences, the company rebranded to ETHZilla in mid-2025, signaling a decisive shift from its pharmaceutical focus to becoming a key player in Ethereum asset accumulation and management. This repositioning aligns with broader institutional trends favoring digital assets, particularly Ethereum, as a cornerstone for future financial systems. Institutional involvement in Ethereum is increasing, reflecting confidence in its scalability and smart contract capabilities. ETHZilla’s transparency through regular updates aims to build investor trust by keeping the market informed on its Ethereum holdings and strategic developments. These developments come as Ethereum continues to evolve with Layer 2 solutions enhancing its scalability and interoperability.
ETHZilla’s bold shift from biotech to Ethereum treasury management signals a new era in digital asset investment.
Peter Thiel’s acquisition of a substantial 7.5% ownership, equivalent to over 11 million shares traded under the ticker ATNF, was disclosed via a recent SEC filing. This move not only underscores Thiel’s growing confidence in Ethereum’s scalability and blockchain potential but also complements his broader Ethereum portfolio, which includes a notable stake in BitMine Immersion, recognized for maintaining one of the largest corporate Ethereum treasuries globally. Such investments reflect a strategic belief in Ethereum’s evolving smart contract ecosystem and Layer-2 scaling solutions, which are increasingly attracting institutional capital.
ETHZilla’s financial maneuvers have been equally significant, having raised upwards of $425 million through private placements aimed at expanding its Ethereum holdings. The company also secured $156 million via senior secured convertible notes, maturing in 2028, to bolster liquidity and support its treasury strategy. These funds are earmarked not only for direct ETH acquisitions but also for yield farming initiatives within decentralized finance protocols and potential iGaming sector expansions, thereby aiming to integrate blockchain assets with regulated financial markets.
The market responded swiftly, with ETHZilla’s shares climbing over 11% during regular trading hours and surging nearly 57% in after-hours following the announcement. This volatility highlights investor enthusiasm for Ethereum-based corporate treasuries, though it also signals the inherent uncertainties tied to such transformative business models. Overall, ETHZilla’s pivot, backed by prominent institutional endorsement and substantial capital inflows, positions it at the forefront of corporate Ethereum treasury management amid an environment of accelerating blockchain adoption.
